May I make mk677 solution with olive oil at home?

Did you buy MK677 raw powder, pills or solutions? Because of the price transparency of the powder and the convenience of quality control, more and more people are now buying MK677 powder. So, if you want to configure your mk677 powder as a solution, what should you do?

Olive oil is a common vegetable oil, which has good safety and rich nutritional value, and is widely used in food, health products and drug carriers. Its fat-soluble properties make it one of the alternative solvents for dissolving some fat-soluble compounds. The purpose of this experiment was to test the dissolution of 1g MK677 powder in olive oil to evaluate the feasibility of its practical application.

Experimental procedure

Preliminary test: Add 2ml olive oil

Add 1g MK677 powder to a clear glass container, followed by 2ml olive oil, and use ultrasonic shock to help separate the mixture and observe.

Observations: Observations showed that the solvent did not appear to be sufficient, and most of the powder showed no signs of dissolution.

Directly increase dosage to 50ml

Since the dissolution of 1g MK677 in olive oil looks very similar to that in grapeseed oil, based on our experience in grapeseed oil experiments, we chose to increase the olive oil directly to 50ml.

After 50ml of olive oil is added, the beaker is also placed in the ultrasonic oscillator. When the solution is fully mixed, observe the state of the mixture.

Observation results: The solution showed a yellow turbidous liquid state, the powder was suspended in the solution, and was not completely dissolved. This indicates that MK677 cannot be completely dissolved even at a dosage of 50ml.

Conclusion

As a vegetable oil, although olive oil has good fat solubility, its ability to dissolve MK677 powder is not good. During the whole experiment, even if the amount of olive oil was increased to 50ml, MK677 still did not dissolve completely, but showed a uniform suspension or precipitation state. This may be due to the chemical properties of MK677 which determine its low solubility in non-polar oil solvents.

Compared with PEG300, DMSO and other solvents, the solubility of olive oil is obviously not ideal. However, due to the safety and natural properties of olive oil, it can still be used as an alternative carrier if it is only used for the preparation of low concentration suspensions. However, olive oil is not ideal for high concentration dissolution requirements.