S23 is a selective androgen receptor modulator (SARM) and is considered to be one of the most potent Sarms currently available. It has effects for bodybuilders to increase muscle mass and improve body composition, while in some cases being studied for male contraception. Here is the basic information about the S23:
Mechanism of action:
S23 promotes muscle synthesis and increased bone density by selectively activating androgen receptors, while inhibiting fat storage. It is also thought to be able to reduce levels of myostatin, which promotes muscle growth.
Purpose:
Increase muscle mass and strength.
Reduce body fat.
It may be used to treat muscular dystrophy and related diseases.
Form: S23 is usually available in raw powder, liquid, or capsule form for oral use.
Is the Sarms S23 safe?
S23 is an experimental selective androgen receptor modulator (SARM) that has a stronger effect than other Sarms, but safety is still a much-discussed topic, especially in the context of long-term use.
Hormone suppression:
Significant inhibition of testosterone: S23 is the most significant of the many Sarms that inhibit testosterone levels, and long-term use may lead to hypogonadism. Because S23 has a strong inhibiting effect on testosterone, late treatment (PCT) is often required after using S23 to help the body return to normal hormone levels.
May cause infertility: Animal studies have shown that S23 temporarily reduces sperm production, possibly affecting fertility.
Side effects:
Androgen side effects: Due to the powerful nature of S23, androgen side effects similar to steroids may occur, such as hair loss, voice thickening, etc., especially at high doses.
Fluctuations in blood pressure: Some users report an increase in blood pressure after using S23.
Liver burden: While SARM generally has less impact on the liver than steroids, S23 still has the potential to cause some stress to the liver, especially if used for a long time or at high doses.
How long will it take to see results with the sarms S23?
After using the S23, users usually start to notice results within two to four weeks, depending on individual differences and conditions of use. Here are some key points:
Initial results:
After 2 weeks of using the S23, some users may start to feel a boost in strength and an increase in endurance, especially when doing high-intensity training.
Notable effects:
By 4 weeks, many users are able to observe more significant muscle growth and body shape improvement, including fat loss and the appearance of muscle lines.
Best results:
In the six to eight week usage cycle, users are usually able to experience the maximum effects of the S23, including significant strength gains and increased muscle mass.
Factors affecting the effect of S23
Individual differences: Each person's physiological response, genes, exercise habits, and diet all affect when the effects appear.
Dose and cycle: Higher doses may speed up the effect, but caution is needed to avoid side effects.
Combine exercise and diet: A proper exercise plan and nutrient intake can enhance the effects of S23, promoting muscle growth and fat loss.
What is the best cycle for S23?
The optimal use cycle of S23 is usually 6 to 8 weeks. This is because S23 is a potent SARM and long-term use may cause hormone suppression and other side effects, so it is very important to control the cycle of use. In fact, how to make a suitable cycle for oneself is related to the following factors:
Maximize the effect:
A 6 - to 8-week cycle provides significant muscle growth and fat reduction while avoiding the potentially serious side effects of long-term use.
Hormone suppression:
S23 is one of the most significant SArms that inhibit testosterone. Prolonged periods of use (more than 8 weeks) may result in deeper hormonal suppression, increasing the difficulty of recovery. Therefore, it is recommended not to use for more than 8 weeks.
Late Treatment (PCT) :
Because S23 is highly hormone-inhibiting, late treatment (PCT) is often required after use to restore the body's natural hormone levels. PCT is usually recommended for 4 to 6 weeks after completing the cycle of use to help testosterone levels recover.
Cycle example
6-week cycle: Recommended for first-time users of S23 to observe physical reactions and effects.
8 week cycle: Suitable for experienced users to get more muscle growth and strength improvement.
Some users may get satisfactory results in a short period of 4 weeks, but it is usually recommended to maintain the period for at least 6 weeks to ensure maximum results.
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How effective is S23 stack with other supplements or SARMs?
The S23 can be used stack with other SARMs, such as the LGD-4033 or MK-2866, and may provide more significant muscle growth and fat reduction effects. This stack helps to utilize the mechanisms of different SARMs to achieve better body shape improvement.
Combining S23 with a fat burning supplement, such as green tea extract or CLA, may enhance the fat loss effect and help improve the efficiency and effectiveness of training.
Adding amino acids (such as BCAA) or electrolyte supplements while using S23 can improve training endurance and speed up the recovery process.
When used in stack, the dosage of each substance needs to be carefully controlled to reduce the potential suppression of hormones.
Is the S23 suitable for women?
The use of S23 in women is still controversial because it is a very potent SARM with significant androgenic properties. Although S23 is mainly used for muscle growth and fat loss, women face a greater risk of side effects when using it, so S23 is generally not recommended for women.
Masculine characteristics: Due to the powerful nature of S23, female use may cause masculine side effects, including coarse voice, increased body hair, hair loss, rough skin, etc. This is due to the strong action of S23 on androgen receptors, resulting in relatively elevated androgen levels in the female body.
Hormone disruption: S23 may not only affect testosterone levels, but may also adversely affect a woman's hormonal balance, interfere with the menstrual cycle, and even cause a temporary or long-term decline in fertility.
Mild SARMs: For female users, milder SARMs, such as MK-2866 (Ostarine) or LGD-4033, may be a more suitable choice. Their androgen effect is weak, and the side effects are less, suitable for women to use muscle toning and fat loss.
In conclusion, although S23 can be used for rapid muscle growth and fat loss, its strong androgenic properties can trigger serious side effects, so it is generally not recommended for women. For women, it may be safer to opt for milder SARMs or other fitness supplements.
What is the recommended dose of S23?
The common dose range for S23 is usually 10 to 30 mg per day, and the specific dosage varies from person to person.
Beginner dose:
For people using S23 for the first time, it is recommended to start at 10 mg/day. This lower dose helps the body adapt and side effects and reactions can be observed.
Intermediate user dose:
Users with some experience can increase the dose to 15-20 mg/day. This dose is generally considered to be within the safe range while providing good muscle growth and fat loss.
Advanced user dose:
For experienced users who cope well with S23, the dose can be increased to 25-30 mg/day. This high dose can bring a stronger effect, but also comes with a greater risk of hormonal suppression and side effects, and needs to be cautious.
Daily divided doses:
Because S23 has a short half-life (about 4 hours), it is recommended to divide the daily dose into two or three doses to maintain a stable concentration in the blood for a more sustained effect.
Dose control:
Because S23 inhibits testosterone levels strongly, it is recommended not to exceed 30 mg/day, and try to limit the cycle of use to 6 to 8 weeks to reduce the potential risk of hormone suppression.
Later treatment (PCT) :
After using S23, PCT is often required to help restore the body's natural hormone levels.
Product Name: S23
CAS:1010396-29-8
MF:C18H13ClF4N2O3
MW: 416.753
Appearance: White powder
Purity: 99.% min
Package: 1g/bag
Test Method: HPLC